Topical application refers to the method of applying substances directly onto the surface of the skin for therapeutic, cosmetic, or pharmaceutical purposes. This method allows for localized treatment of skin conditions or delivery of active ingredients to specific areas of the body without affecting the entire system. Examples of topical applications include creams, gels, ointments, lotions, and patches. Topical application is commonly used in dermatology, skincare, pain management, and wound healing.